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Class: BicanAnnotation

URI: PCL:0010001

classDiagram class BicanAnnotation click BicanAnnotation href "../BicanAnnotation" Annotation <|-- BicanAnnotation click Annotation href "../Annotation" BicanAnnotation : author_annotation_fields BicanAnnotation --> "0..1" Any : author_annotation_fields click Any href "../Any" BicanAnnotation : cell_fullname BicanAnnotation : cell_ids BicanAnnotation : cell_label BicanAnnotation : cell_ontology_term BicanAnnotation : cell_ontology_term_id BicanAnnotation --> "0..1" CellTypeEnum : cell_ontology_term_id click CellTypeEnum href "../CellTypeEnum" BicanAnnotation : cell_set_accession BicanAnnotation : cells BicanAnnotation --> "*" Cell : cells click Cell href "../Cell" BicanAnnotation : labelset BicanAnnotation : marker_gene_evidence BicanAnnotation : negative_marker_gene_evidence BicanAnnotation : parent_cell_set_accession BicanAnnotation : rationale BicanAnnotation : rationale_dois BicanAnnotation : reviews BicanAnnotation --> "*" Review : reviews click Review href "../Review" BicanAnnotation : synonyms BicanAnnotation : transferred_annotations BicanAnnotation --> "*" AnnotationTransfer : transferred_annotations click AnnotationTransfer href "../AnnotationTransfer"

Inheritance

Slots

Name Cardinality and Range Description Inheritance
cell_set_accession 1
String
An identifier that can be used to consistently refer to the set of cells bein... direct
parent_cell_set_accession 0..1
String
A list of accessions of cell sets that subsume this cell set direct
transferred_annotations *
AnnotationTransfer
direct
cells *
Cell
By convention this is only used for annotation transfer labelsets direct
negative_marker_gene_evidence *
String
Gene names explicitly used as evidence, which MUST be in the matrix of the An... direct
labelset 1
String
The unique name of the set of cell annotations Annotation
cell_label 1
String
This denotes any free-text term which the author uses to annotate cells, i Annotation
cell_fullname 0..1
String
This MUST be the full-length name for the biological entity listed in `cell_l... Annotation
cell_ontology_term_id 0..1
CellTypeEnum
This MUST be a term from either the Cell Ontology (https://www Annotation
cell_ontology_term 0..1
String
This MUST be the human-readable name assigned to the value of 'cell_ontology_... Annotation
cell_ids *
String
Cell barcode sequences/UUIDs used to uniquely identify the cells within the A... Annotation
rationale 0..1
String
The free-text rationale which users provide as justification/evidence for the... Annotation
rationale_dois *
String
Annotation
marker_gene_evidence *
String
Gene names explicitly used as evidence, which MUST be in the matrix of the An... Annotation
synonyms *
String
List of synonyms Annotation
reviews *
Review
Annotation
author_annotation_fields 0..1
Any
A dictionary of author defined key value pairs annotating the cell set Annotation

Usages

used by used in type used
BicanTaxonomy annotations range BicanAnnotation

Identifier and Mapping Information

Schema Source

  • from schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS

Mappings

Mapping Type Mapped Value
self PCL:0010001
native cell_annotation_schema:BicanAnnotation

LinkML Source

Direct

name: Bican_Annotation
from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
is_a: Annotation
slots:
- cell_set_accession
- parent_cell_set_accession
- transferred_annotations
- cells
- negative_marker_gene_evidence
class_uri: PCL:0010001

Induced

name: Bican_Annotation
from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
is_a: Annotation
attributes:
  cell_set_accession:
    name: cell_set_accession
    description: An identifier that can be used to consistently refer to the set of
      cells being annotated, even if the cell_label changes.
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    alias: cell_set_accession
    owner: Bican_Annotation
    domain_of:
    - Bican_Annotation
    range: string
    required: true
  parent_cell_set_accession:
    name: parent_cell_set_accession
    description: A list of accessions of cell sets that subsume this cell set. This
      can be used to compose hierarchies of annotated cell sets, built from a fixed
      set of clusters.
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    slot_uri: RO:0015003
    alias: parent_cell_set_accession
    owner: Bican_Annotation
    domain_of:
    - Bican_Annotation
    range: string
  transferred_annotations:
    name: transferred_annotations
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    alias: transferred_annotations
    owner: Bican_Annotation
    domain_of:
    - Bican_Annotation
    range: AnnotationTransfer
    multivalued: true
  cells:
    name: cells
    description: By convention this is only used for annotation transfer labelsets.  It
      MUST not be combined with the 'cell_ids' field.
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    alias: cells
    owner: Bican_Annotation
    domain_of:
    - Bican_Annotation
    range: Cell
    multivalued: true
  negative_marker_gene_evidence:
    name: negative_marker_gene_evidence
    description: Gene names explicitly used as evidence, which MUST be in the matrix
      of the AnnData/Seurat file
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    alias: negative_marker_gene_evidence
    owner: Bican_Annotation
    domain_of:
    - Bican_Annotation
    range: string
    multivalued: true
  labelset:
    name: labelset
    description: "The unique name of the set of cell annotations. \nEach cell within\
      \ the AnnData/Seurat file MUST be associated with a 'cell_label' value in order\
      \ for this to be a valid 'cellannotation_setname'."
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    slot_uri: CAS:has_labelset
    alias: labelset
    owner: Bican_Annotation
    domain_of:
    - Annotation
    range: string
    required: true
  cell_label:
    name: cell_label
    description: "This denotes any free-text term which the author uses to annotate\
      \ cells, i.e. the preferred cell label name used by the author. Abbreviations\
      \ are exceptable in this field; refer to 'cell_fullname' for related details.\
      \ \nCertain key words have been reserved:\n- `'doublets'` is reserved for encoding\
      \ cells defined as doublets based on some computational analysis\n- `'junk'`\
      \ is reserved for encoding cells that failed sequencing for some reason, e.g.\
      \ few genes detected, high fraction of mitochondrial reads\n- `'unknown'` is\
      \ explicitly reserved for unknown or 'author does not know'\n- `'NA'` is incomplete,\
      \ i.e. no cell annotation was provided"
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    slot_uri: rdfs:label
    alias: cell_label
    owner: Bican_Annotation
    domain_of:
    - Annotation
    range: string
    required: true
  cell_fullname:
    name: cell_fullname
    description: "This MUST be the full-length name for the biological entity listed\
      \ in `cell_label` by the author. (If the value in `cell_label` is the full-length\
      \ term, this field will contain the same value.) \nNOTE: any reserved word used\
      \ in the field 'cell_label' MUST match the value of this field. \n\nEXAMPLE\
      \ 1: Given the matching terms 'LC' and 'luminal cell' used to annotate the same\
      \ cell(s), then users could use either terms as values in the field 'cell_label'.\
      \ However, the abbreviation 'LC' CANNOT be provided in the field 'cell_fullname'.\
      \ \n\nEXAMPLE 2: Either the abbreviation 'AC' or the full-length term intended\
      \ by the author 'GABAergic amacrine cell' MAY be placed in the field 'cell_label',\
      \ but as full-length term naming this biological entity, 'GABAergic amacrine\
      \ cell' MUST be placed in the field 'cell_fullname'."
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    slot_uri: skos:preflabel
    alias: cell_fullname
    owner: Bican_Annotation
    domain_of:
    - Annotation
    range: string
  cell_ontology_term_id:
    name: cell_ontology_term_id
    description: 'This MUST be a term from either the Cell Ontology (https://www.ebi.ac.uk/ols/ontologies/cl)
      or from some ontology that extends it by classifying cell types under terms
      from the Cell Ontology

      e.g. the Provisional Cell Ontology (https://www.ebi.ac.uk/ols/ontologies/pcl)
      or the Drosophila Anatomy Ontology (DAO) (https://www.ebi.ac.uk/ols4/ontologies/fbbt).


      NOTE: The closest available ontology term matching the value within the field
      ''cell_label'' (at the time of publication) MUST be used.

      For example, if the value of ''cell_label'' is ''relay interneuron'', but this
      entity does not yet exist in the ontology, users must choose the closest available
      term in the CL ontology. In this case, it''s the broader term ''interneuron''
      i.e.  https://www.ebi.ac.uk/ols/ontologies/cl/terms?obo_id=CL:0000099.'
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    slot_uri: RO:0002473
    alias: cell_ontology_term_id
    owner: Bican_Annotation
    domain_of:
    - Annotation
    range: CellTypeEnum
  cell_ontology_term:
    name: cell_ontology_term
    description: This MUST be the human-readable name assigned to the value of 'cell_ontology_term_id'
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    alias: cell_ontology_term
    owner: Bican_Annotation
    domain_of:
    - Annotation
    range: string
  cell_ids:
    name: cell_ids
    description: Cell barcode sequences/UUIDs used to uniquely identify the cells
      within the AnnData/Seurat matrix. Any and all cell barcode sequences/UUIDs MUST
      be included in the AnnData/Seurat matrix.
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    slot_uri: CAS:has_cellid
    alias: cell_ids
    owner: Bican_Annotation
    domain_of:
    - Annotation
    range: string
    multivalued: true
  rationale:
    name: rationale
    description: "The free-text rationale which users provide as justification/evidence\
      \ for their cell annotations. \nResearchers are encouraged to use this field\
      \ to cite relevant publications in-line using standard academic citations of\
      \ the form `(Zheng et al., 2020)` This human-readable free-text MUST be encoded\
      \ as a single string.\nAll references cited SHOULD be listed using DOIs under\
      \ rationale_dois. There MUST be a 2000-character limit."
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    alias: rationale
    owner: Bican_Annotation
    domain_of:
    - Annotation
    range: string
  rationale_dois:
    name: rationale_dois
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    alias: rationale_dois
    owner: Bican_Annotation
    domain_of:
    - Annotation
    range: string
    multivalued: true
  marker_gene_evidence:
    name: marker_gene_evidence
    description: Gene names explicitly used as evidence, which MUST be in the matrix
      of the AnnData/Seurat file
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    alias: marker_gene_evidence
    owner: Bican_Annotation
    domain_of:
    - Annotation
    range: string
    multivalued: true
  synonyms:
    name: synonyms
    description: List of synonyms
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    alias: synonyms
    owner: Bican_Annotation
    domain_of:
    - Annotation
    range: string
    multivalued: true
  reviews:
    name: reviews
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    alias: reviews
    owner: Bican_Annotation
    domain_of:
    - Annotation
    range: Review
    multivalued: true
  author_annotation_fields:
    name: author_annotation_fields
    description: A dictionary of author defined key value pairs annotating the cell
      set. The names and aims of these fields MUST not clash with official annotation
      fields.
    from_schema: https://cellular-semantics.sanger.ac.uk/ontology/CAS
    rank: 1000
    alias: author_annotation_fields
    owner: Bican_Annotation
    domain_of:
    - Annotation
    range: Any
class_uri: PCL:0010001